Drug Standards
Apexbio Technology LLC Chlorambucil 305-03-3 10mM (in 1mL DMSO)
Chlorambucil (CAS 305-03-3) is an alkylating chemotherapeutic agent belonging to the nitrogen mustard class Its primary mechanism involves forming crosslinks within DNA strands both intra- and inter-strand crosslinks resulting in impaired DNA replication and transcription ultimately inducing cell death In vitro studies showed that chlorambucil potently inhibits human microvascular endothelial cells (IC 0 53 M) and exhibits cytotoxic activities against glioma cell lines such as SF767 (IC 114 M) and U87-MG (IC 96 M) Chlorambucil is widely used in research settings to investigate cell apoptosis DNA damage and lymphoid malignancies like chronic lymphocytic leukemia (CLL)
eMolecules 57584-69-7 | 5-FLUORO-1H-INDEN-2(3H)-ONE | AstaTech | MFCD09743873 | 150.152 | C9H7FO | 95.000 | Fc1ccc2CC(=O)Cc2c1 | 0.1g | 869676570
5-FLUORO-1H-INDEN-2(3H)-ONE | AstaTech | 57584-69-7 | MFCD09743873 | 150.152 | C9H7FO | 95.000 | Fc1ccc2CC(=O)Cc2c1 | 0.1g | 869676570
eMolecules 518-28-5 | Medchem Express | Podofilox | 100mg | 446265946 | HY-15552 | MFCD00075290 | 414.41 | C22H22O8
Medchem Express | Podofilox | 100mg | 446265946 | HY-15552 | 518-28-5 | MFCD00075290 | 414.410 | C22H22O8
eMolecules 1215767-66-0 | Medchem Express | Ketorolac-d5 | 1mg | 559839861 | HY-B0580S | MFCD08460946 | 260.304 | C15H13NO3
Medchem Express | PF 1022A | 5mg | 446261126 | HY-12361 | 133413-70-4 | MFCD00894026 | 949.196 | C52H76N4O12
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Cayman Chemical MeloxIcam-d3 500ug
An internal standard for the quantification of meloxicam by GC- or LC-MS
Selleck Chemical LLC Valganciclovir HCl 10mg 175865-59-5
Valganciclovir HCl is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Tacedinaline10mg
Tacedinaline (CI994, PD-123654, GOE-5549, Acetyldinaline) is a selective class I HDAC inhibitor with IC50 of 0.9, 0.9, 1.2, and >20 ?M for human HDAC 1, 2, 3, and 8, respectively. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical Glycopyrrolate 10mg
A mAChR antagonist (Kis = 0.42, 1.77, 0.52, 0.78, and 1.29 nM for the M1-M5 receptors, respectively); induces relaxation of precontracted isolated human bronchi at 0.01, 0.1, or 1 µM; reduces post-prandial gastric antral motility in dogs at 0.01 mg/kg; inhibits salivation in a rat model of pilocarpine-induced sialorrhea (ED50 = 0.74 UG/kg)
Cayman Chemical R-CrIzotInIb 100mg
A dual inhibitor of c-Met and ALK (IC50s = 8 and 20 nM, respectively, in a cell-based assay); selective for c-Met and ALK over several other receptor and non-receptor tyrosine kinases, including Ron, Tie2, Abl, LCK, and VEGFR2 (IC50s = 0.08, 0.448, 1.159, 2.741, and >10 µM, respectively); selectively inhibits the proliferation of cancer cell lines with MET amplifications over cancer cell lines with MET or EGFR mutations (IC50s = 5-10, 472-1,284, and 767-787 nM, respectively); induces apoptosis in MET-amplified EBC-1 and NCI H1993 cells at 100 nM; reduces tumor volume in an EBC-1 mouse xenograft model at 25 mg/kg
Medchemexpress LLC Rosuvastatin lactone | 503610-43-3 | MFCD16621107 | 98.6% | C22H26FN3O5S | 10MG
Rosuvastatin lactone is the lactone metabolite of rosuvastatin supplied as an analytical standard for research use only. It is intended for metabolite identification, quantification, and analytical method development in biochemical and pharmaceutical research. The material is provided as a solid with a reported purity of approximately 98.6% and the molecular formula C22H26FN3O5S (MW 463.52 g/mol).
- Intended for research and analytical use only.
- High purity (98.6%) suitable for analytical assays.
- Molecular formula C22H26FN3O5S and molecular weight 463.52 g/mol.
- Available in milligram-scale packages for standards and method development.
- Supplied with datasheet and certificate of analysis for batch verification.
AdipoGen Suramin Hexasodium salt, 129-46-4, MFCD00210217, 50 mg
MF: C51H34N6O23S6 . 6Na, MW: 1429.180, ≥98%, Appearance: White to off-white powder. Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor.
TARGETMOL CHEMICALS INC NIVOLUMAB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Nivolumab anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune checkpoint inhibitory and antineoplastic activities. purity: 98%
Sigma Aldrich Fine Chemicals Biosciences Clindamycin palmitate hydrochloride United States Pharmacopeia (USP) Reference Standard | 25507-04-4 | 500MG
Clindamycin palmitate hydrochloride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 699.85 | 25507-04-4 | 500MG
Selleck Chemical LLC Poziotinib (HM781-36B) 5mg 1092364-38-9 NOV120101
Poziotinib (HM781-36B, NOV120101) is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Poziotinib also induces apoptosis and G1 cell cycle arrest. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.